Compared with HCs, overall pediatric sepsis patients had significant longer PT, APTT, but shorter TT, higher INR, fibrinogen, D-dimer and FDP level, yet lower antithrombin III level, in addition, the levels of TAT, PIC and t-PAIC were significantly increased in overall pediatric sepsis patients (Table 1). Here, SERPINC1 is linked to Sepsis.