HAMP and metabolic disease: In addition, the increase in CRP means that the body is in an inflammatory state, and inflammatory cytokines can stimulate the liver to synthesize hepcidin,37 which can not only bind with iron transport‐related proteins on the surface of duodenal cells to weaken its effect of transferring iron but also regulate the transport process of iron through intestinal mucosa, inhibit the absorption of iron and the release of iron in cells, resulting in iron metabolism disorder and eventually leading to anemia.38, 39, 40