We analyzed the expression level of CSMD1 in the subtypes of the TCGA-GBM cohort, as the mesenchymal subtype is more paramount in GBM than in LGG and we revealed that CSMD1 was downregulated in the mesenchymal GBM samples compared to other GBM subtypes (Supplementary Fig. 2P). Here, CSMD1 is linked to glioblastoma.