Previous study by Bevilacqua JA et al. 2020 reported that the nine most-frequent LGMD-causing genes were CAPN3; DYSF; SGCG; SGCA; SGCB; SGCD; FKRP; ANO5; TCAP and GAA [38]. The gene discussed is SGCB; the disease is limb-girdle muscular dystrophy.