Supporting this finding, analysis of the TCGA database revealed strong positive correlations between the expression of TNFSF15 and NF-κB pathway-related genes NFKB1, NFKB2 and RELB, as well as a key marker gene associated with T cell activation ICAM1 in human GBM samples [63] (Fig. 6F-I). This evidence concerns the gene TNFSF15 and glioblastoma.