In previous reports, the risk factors for carcinogenesis of AIH were two or more recurrences [18], male sex, portal hypertension, history of blood transfusion, immunosuppressive therapy for more than 3 years, therapeutic failure, liver cirrhosis for more than 10 years [19], advanced age, and elevated ALT levels during treatment [14, 17, 20]; however, there is still no consensus. The gene discussed is GPT; the disease is portal hypertension.