Microfibril-associated protein 3-like (MFAP3L), belonging to the MAGP family, is involved in regulating cell proliferation, migration, and invasion in cancer, as reported in previous studies.28 Our findings indicated a strong signal of Mfap3l in interdigit regions of the limbs in WT/WT, moderate expression in Q50R/WT, and a slight distal expression in Q50R/Q50R at E11.5 (Fig. 6b). Here, MFAP3L is linked to cancer.