Indeed, through a joint bioinformatics analysis with TCGA and GTEx database, we found that RCC1 is more abundantly expressed in tumor tissues compared to adjacent normal tissues in thymoma (THYM, T/N Ratio = 10.73), glioblastoma (GBM, T/N Ratio = 7.44), large B-cell Lymphoma (DLBC, T/N Ratio = 7.60), and sarcoma (SARC, also referred as STS, T/N Ratio = 5.86). The gene discussed is RCC1; the disease is telomere syndrome.