When the staining intensity of ccRCC patients stratified into groups with low or high levels of TRIB3 or PLIN2 expression, as determined based on median H-score values, low TRIB3 staining was confirmed to be associated with weaker PLIN2 staining in these tumors, while higher TRIB3 levels were associated with more intense PLIN2 staining (Fig. 8A–C). Here, PLIN2 is linked to nonpapillary renal cell carcinoma.