In SM, the OPLS‐regression found no significant correlation between the “Glucose‐insulin‐AMPK” community and BMI (R2 = 0.18 and p > 0.05) but there was a clear separation with regards to T2D with R2 of 0.23 and p‐value of <0.01 after cross‐validation. This evidence concerns the gene INS and type 2 diabetes mellitus.