Importantly, miR-125b overexpression reversed the DDP resistance in non-small cell lung cancer (NSCLC) cells and inhibited the autophagy by targeting retinoic acid receptor-related orphan receptor A (RORA) and downstream autophagy-related genes BCL2 Interacting Protein 3 Like (BNIP3L). This evidence concerns the gene RORA and non-small cell lung carcinoma.