Recently, accumulating evidence has demonstrated that NSCLC is an inflammation-related cancer [4–6], and the overexpression of inflammatory cytokines or mediators in NSCLC microenvironment can induce the cancer cell proliferation, migration and invasion [7–10], but the precise mechanism, e.g., IL-17-mediated NSCLC metastasis has not been characterized. The gene discussed is IL17A; the disease is non-small cell lung carcinoma.