Also, KLF10 (TGF-β inducible early gene 1, EGR1) is a DNA-binding transcriptional regulator with a tri-C2H2 zinc finger domain that binds to a SP1 site on DNA and interacts with other regulatory transcription factors to suppress gene expression, with anti-proliferation effect and inducing cancer cell apoptosis [81,82]. Here, EGR1 is linked to cancer.