HMOX1 and type 2 diabetes mellitus: Our experimental results showed that the mRNA expression levels of Nrf2, HO-1, NQO1 and γ-GCS in the livers of T2DM rats were significantly decreased, and after treatment with taurine, the mRNA expression levels of Nrf2, HO-1, NQO1 and γ-GCS of rat livers were significantly increased.