Catenin Alpha 1 (CTNNA1) is integral to the cadherin-catenin complex, crucial for cell-cell adhesion, with disruptions in its function or phosphorylation potentially leading to cardiomyocyte detachment and unique forms of cardiomyopathy and increased vulnerability to fatality after cardiac stress (28). The gene discussed is CTNNA1; the disease is cardiomyopathy.