Even though BrS can exhibit autosomal dominant inheritance, it is not easy to identify the phenotype and genotype in a family thoroughly.<h4>Case</h4>We report the case of a 20-year-old man with variants in <i>SCN5A</i> and <i>RyR2</i> genes who was resuscitated from sudden cardiac death during sleep due to a ventricular fibrillation. This evidence concerns the gene SCN5A and ventricular fibrillation.