The results showed increased TLCD1 mRNA expression in most cancer types compared to normal samples, including BLCA, BRCA, CESC, COAD, DLBC, GBM, LIHC, LUAD, LUSC, OV, PAAD, PRAD, READ, STAD, THCA, THYM, UCEC, and UCS, while decreased expression was observed in KIRC and LAML. This evidence concerns the gene TLCD1 and cancer.