Elevated expression of RAB1A andRAB1B genes have implications in various cancer types, including colorectal cancer,9 hepatocellular cancer,10 gliomas,11 tongue carcinomas, prostate cancer12 forRAB1A and colorectal cancer,13 hepatocellular cancer,14 and prostate cancer12 forRAB1B. Rab1A in human cancer is highly studied in comparison to Rab1B as abnormal expression of Rab1A activates mTORC1 signalling, promoting tumour growth, invasion and ultimately cancer progression.9 Rab1 proteins are also involved in the pathogenesis of Parkinson’s disease, characterized by accumulation of α-synuclein. The gene discussed is RAB1B; the disease is hepatocellular carcinoma.