CD8B and neoplasm: Other studies with similar tumor models demonstrated higher tumor mass infiltration by bone marrow-derived CD11b+ Gr-1int/dull Ly-6Chi macrophages than CD11b+Gr-1hiLy-6Cint neutrophils, suggesting that CD11b+ Gr-1int/dull Ly-6Chi macrophages could dominate the tumor microenvironments in these tumors.65 In accordance with these reports, we identified statistically significant high levels of CD11b+ and CD11c+ cells but moderately higher density of CD8b+ cytotoxic T cells compared to the untreated cohort in our immune-competent tumor model.