To achieve such information, we double-immunolabeled SRSF2 WT/Mut MOLM14 and OCI-AML2 cells and primary AML cells before and after exposure to RKI-1447 with tubulin and laminB1, which delineate the nuclear membrane, and visualized the cells by 3D confocal light microscopy. This evidence concerns the gene SRSF2 and acute myeloid leukemia.