Our data imply that certain B-cell panels, such as CD20−AC, unsw mem %lymphocyte, CD20− %lymphocyte, CD20 on IgD+ CD38−, CD27 on IgD+ CD24+, CD27 on IgD− CD38br, CD27 on IgD− CD38dim, CD38 on naive-mature B cell, and IgD on IgD+ CD38−unsw mem, are related to an elevated risk of psoriasis. This evidence concerns the gene CD24 and psoriasis.