Conversely, five traits showed protective connections with psoriasis: CD11c+ HLA-DR++ monocyte AC (IVW: OR 0.9992, 95% CI 0.9985–0.9999; p = 3.268812e−02), CD62L− DC %DC (IVW: OR 0.9962, 95% CI 0.9948–0.9977; p = 2.802277e−07), HLA-DR on myeloid DC (IVW: OR 0.9983, 95% CI 0.9970–0.9996; p = 1.288528e−02), HLA-DR on plasmacytoid DC (IVW: OR 0.9988, 95% CI 0.9978–0.9998; p = 1.778885e−02), HLA-DR on DC (IVW: OR 0.9984, 95% CI 0.9973−0.9995; p = 3.969029e−03). This evidence concerns the gene ITGAX and psoriasis.