KLK3 and adenoma: The use of the new thulium fiber laser (TFL) in enucleation of the prostate (ThuFLEP) was first introduced in 2018 by Enikeev et al [4] who demonstrated that its efficacy was not inferior to TURP but had a better safety profile and higher decrease of prostate-specific antigen (PSA) value, showing its superiority in more complete removal of adenoma.