Hb: Hemoglobin; TLC: Total Leucocyte Count; Cr: Serum Creatinine; SGOT: Serum Glutamic Oxaloacetic Transaminase; SGPT: Serum Glutamic Pyruvic Transaminase; RBC: Red Blood Cells; ESR: Erythrocyte Sedimentation Rate; CRP: C-Reactive Protein; ANA by IF: Anti-nuclear Antibody by Immunofluorescence; 1:320: indicates the titre of ANA by IF; 2+: indicates the strength of immunofluorescence; speckled: indicates the pattern of immunofluorescence; ENA: Extractable Nuclear Antigen; ScL-70: Scleroderma antibody/Anti Topoisomerase Antibody. The gene discussed is CRP; the disease is scleroderma.