Table 2 shows the results for Aβ42/40 ratio. The model with the covariates and focal predictors (blood glucose, HbA1c, and T2D) accounted for 6%, Wald χ2(24) = 75.11, p < .001, of the variation in Aβ42/40 ratio, and the incremental variance due the focal predictors was < 1%, Wald χ2(3) = 0.65, p = .89. None of the focal predictors were significantly related to Aβ42/40 ratio. Among the covariates, Mexican American participants generally had greater values for Aβ42/40 ratio (b = .42, p < .001, β = .37) as did participants with APOE4 positivity (b = .23, p < .001, β = .20). Here, APOE is linked to type 2 diabetes mellitus.