CEBPA and Hepatic steatosis: However, given that hepatocyte CEBPA knockout, which enhances liver fibrosis, is not always accompanied by exacerbated fatty liver during MASH and that it even enhances CCl4-induced liver fibrosis — accompanied by decreased hepatic lipids — it is less likely that hepatocyte CEBPA knockout promotes liver fibrosis depending on its effect on increasing hepatic lipids.