As KAT6B has been implicated in mitochondrial function in Alzheimer’s disease (14) and aspects of the KAT6B-related KAT6A syndrome have been proposed to arise from mitochondrial dysfunction (15), we assessed mitochondrial morphology and function across SBBYSS HEK293T cell lines. The gene discussed is KAT6B; the disease is early-onset autosomal dominant Alzheimer disease.