In Fig. 10a, the data from CAD patients (indicated by black dots) exhibited a predominant distribution on the upper-right side of the slope, because of their higher PCSK9 concentration (409.4 ng/mL) and higher phosphorylation of signaling proteins compared with healthy donors whose distribution was on the lower-left side (indicated by pink dots, 290.1 ng/mL). The gene discussed is PCSK9; the disease is coronary artery disorder.