To track induction of the memory-like NK cells and their prolonged existence following the combination therapy with and without tumor inoculation, we employed a prophylactic protocol setting in which two cycles of either the PBS or the STING-LNPs and CpG-ODNs combination therapy was intravenously administered on days 0 and 4 (Fig. 5B). This evidence concerns the gene STING1 and neoplasm.