These results also showed a stronger correlation between FGF2 and the pathways related to cancer stemness (Fig. S15A-B) and JAK-STAT pathway (Fig. S15C) in FGFR1 high and medium groups compared to FGFR1 low groups, highlighting the importance of FGFR1 overexpression in enhancing cancer stemness and related pathways through FGF2. The gene discussed is SOAT1; the disease is cancer.