In a previous study we identified DDX5 as one of the factors associated with the Sindbis virus (SINV) replication complex by dsRNA-IP coupled to mass spectrometry (DRIMS) and observed that DDX5 knockdown (KD) significantly reduces GFP expression in human colorectal carcinoma (HCT116) cells infected with a GFP-expressing SINV [26]. Here, DDX5 is linked to colorectal carcinoma.