We next utilized scRNA-seq to uncover transcriptional heterogeneity among the L-IC-containing DN3 population within the context of Tal1/Lmo2-induced primary mouse leukemias, T-ALL#1 (Fig. 1B) and T-ALL#2 (Supplementary Fig. 2A). The gene discussed is LMO2; the disease is acute lymphoblastic leukemia.