In addition, the interactions between miRNAs and Atg7 may regulate ischemic brain injury121, cerebral I/R injury122,123, neuronal apoptosis124, M. tuberculosis infection125,126, allergic asthma127, systemic lupus erythematosus128, sepsis129 and sepsis-induced acute kidney injury (AKI)130, nonobstructive azoospermia131, urethral stricture and urethral fibrosis132, hypoxia-induced pulmonary hypertension133, hepatic I/R injury134, hepatitis B virus replication135, inflammatory bowel disease136, diabetes mellitus137, pancreatic ductal adenocarcinoma (PDAC)138, and senile cataracts139. This evidence concerns the gene ATG7 and acute kidney injury.