Our research findings (Fig. S6C) revealed a positive correlation between LINC-PINT expression and TMB in several cancer types, including Adrenocortical Carcinoma (ACC), Thymoma (THYM), SKCM, and Esophageal Carcinoma (ESCA) (correlation coefficient > 0, P < 0.05). This evidence concerns the gene LINC-PINT and carcinoma of esophagus.