PRKN and Parkinson disease: The average age at onset of first symptom of PD in PRKN-PD patients with information about the prevalence of at least one feature of motor complications (n = 107) was 29.72 ± 11.34 years, in comparison to 43.53 ± 5.68 years in early-onset PD (n = 72) (Supplementary Fig. 8).