The GSE14520 dataset showed that the expression levels of CCR1, CCR2, CCR3, CCR5, CCR7, and CCR8 in the HCC tissues were significantly lower than that of the para-carcinoma liver tissues, whereas the expression of CCR6 and CCR9 was higher in the HCC tissues (Figure 2A). Here, CCR5 is linked to hepatocellular carcinoma.