In TCGA cohort, CCR1 (P=0.023), CCR2 (P<0.001), CCR4 (P=0.007), CCR5 (P<0.001), CCR6 (P<0.001), CCR7 (P<0.001), CCR8 (P=0.029), and CCR9 (P=0.015) were observed to be associated with the RFS of the HCC patients (Supplementary Figure 2K, 2L, 2N–2S), while no prognostic significance was found for CCR3 and CCR10 (Supplementary Figure 2M, 2T). This evidence concerns the gene CCR6 and hepatocellular carcinoma.