A thyroid storm is a menacing and life-threatening culmination of hyperthyroidism, where the body’s thyroid gland overproduces thyroid hormones to an extreme degree.[1] This condition, while rare, represents a critical medical emergency that demands immediate recognition and intervention.[1] A thyroid storm is characterized by severe symptoms that affect multiple organ systems, including the heart, nervous system, and gastrointestinal tract. The gene discussed is TG; the disease is thyroid crisis.