SLCO1B1 and Myalgia: The pragmatic SLCO1B1 genotype-informed statin therapy (GIST) trial randomised patients who had discontinued any statins due to myalgia to SLCO1B1 genotype guided therapy (rosuvastatin, pravastatin, or fluvastatin for SLCO1B1*5 carriers and any statin for non-carriers) or standard care (Peyser et al., 2018).