Specifically, we want to highlight glycan-regulating proteins linked to macrophages, which hold promise as therapeutic targets in pulmonary fibrosis and sarcoidosis using as examples fucosyltransferases (FUTs), neuraminidase-1 (NEU1), and chitinase-1 (CHIT1) (see Table 1). The gene discussed is NEU1; the disease is pulmonary fibrosis.