(33) studied the expression of several antigens in tumor cells from 7 GBM patients, before and after a single infusion of EGFR-targeted CAR-T cells, observing in all of them a significant decrease in EGFR expression, but an important increase in several other antigens with known immunosuppressor functions (CD8, GRZMB, CD25, IDO1, PDL1, and FoxP3). Here, IDO1 is linked to neoplasm.