In a study of non-small cell lung cancer (NSCLC), high expression of miR-4443 was found to negatively regulate the m6A modification of FSP1 induced by methyltransferase METTL3 to inhibit cisplatin-induced ferroptosis, thereby conferring cisplatin resistance in NSCLC. Here, AIFM2 is linked to non-small cell lung carcinoma.