TIAM1 and thyroid gland carcinoma: However, ALKBH5 expression is decreased in thyroid cancer, and ferroptosis can be induced by overexpression of ALKBH5 along the m6A-TIAM1-NRF2/HO-1 axis, thereby inhibiting the progression of thyroid cancer, suggesting that ALKBH5 may be a potential target molecule for the treatment and diagnosis of thyroid cancer (Li et al., 2023).