PLAT and Stroke: As one of the three major diseases that threaten human health, stroke is considered the second leading cause of death and the third leading cause of disability worldwide.1 Current treatment strategies for acute ischaemic stroke (AIS) mainly focus on recanalization techniques, including intravenous or intraarterial administration of recombinant tissue plasminogen activator (r-tPA) and mechanical endovascular therapies.2 However, these methods inevitably result in poor prognosis.