NR1H3 and infection: Inflammatory mediators, such as cytokines and chemokines are important for the recruitment of immune cells to sites of infection and injury.[2] To investigate the role of endogenous LXRα‐dependent pathways in modulating inflammation in vivo, we used a validated model of murine peritoneal inflammation using three different challenges;[46, 47] LPS, zymosan or thioglycollate were injected into cohorts of WT and LXRα deficient mice.