HK1 and infection: In neuronal models, the proteins that play pivotal roles in glycolytic regulation (hexokinase [HK1], phosphofructokinase [PFKP/PFKL], and pyruvate kinase [PKM]) were upregulated after infection (Fig. 2D, bold); while in NSC-derived cells, lactate dehydrogenase-associated LDHAL6B was down-regulated.