ACE2 and viral infectious disease: SARS-CoV-2 is able to infect human cells and tissues mainly through their expression of angiotensin-converting enzyme 2 (ACE2), the main port of entry for the virus2,7,8; however, other receptors have been described as secondary for viral infection, such as TPMRS22, NPR1, and BSG/CD1479,10 Once inside the cell, SARS-CoV-2 then alters cell function at the proteomic level at minimum, often resulting in tissue dysfunction and damage.