SEMA7A and neoplasm: However, in C3H mice bearing Sema7a -WT-re-expressing SCC7- Sema7a-KO xenograft tumors, the combined treatment with 2F-Fuc and anti-PD-L1 antibodies conspicuously suppressed tumor growth and expansion, as confirmed by the tumor observation and growth curves of the xenograft tumors (Fig. 8g–i).