COL1A2 and osteogenesis imperfecta: We screened for nine OI-causative genes: BMP1, COL1A1, COL1A2, CRTAP, FKBP10, IFITM5, P3H1, PPIB, and SERPINF1. Allele frequencies were evaluated based on the Genome Aggregation Database, Human Genetic Variation Database, Japanese Multi Omics Reference Panel, and GEnome Medical alliance Japan Whole Genome Aggregation Panel.