To this end, we executed a targeted analysis of tagging SNPs in core autophagy gene ATG16L1 using available data from 304 untreated HIV-1-infected men-who-have-sex-with-men (MSM), including genotyping analyses performed with Illumina’s Infinium HumanHap 300 BeadChip, within the Amsterdam Cohort Studies (ACS) on HIV infection and AIDS (Fig. 1a, b)31. This evidence concerns the gene ATG16L1 and AIDS.