In C12, the LPS expression in all the four breast cancer subtypes positively correlated with tumor markers, especially IFI6, and the expression of immune markers such as CD68 was negatively correlated with LPS in all the four breast cancer subtypes except LA (lower half of Fig. 5k, Supplementary Fig. 7d and Supplementary Table 8). The gene discussed is IFI6; the disease is breast cancer.