The treatment takes several parts: The treatment of heart failure (HF) (beta-blocker, angiotensin-converting enzyme (ACE) inhibitor, or angiotensin II receptor antagonist (ARA II), sodium-glucose cotransporter 2 (SGLT2) inhibitors, or others), which represents the main component, must be used with caution given the risk of complications and harmful drug interactions. The gene discussed is ACE; the disease is heart failure.