UCN-1, the first UCN discovered, plays a role in endometrial cancer progression (Owens et al. 2017), stress-induced gastrointestinal dysfunction (Ayyadurai et al. 2017), gastrointestinal motor function, and the processing of visceral pain (Martinez et al. 2004; Yin et al. 2008). This evidence concerns the gene UCN and endometrial cancer.