Additionally, NTN1 can also regulate the expression of c‐Myc by activating the two signal pathways NTN1/NEO1/FAK/ITGB4 β1 and NTN1/UNC5B/NEO1/Gsk3α/β, so as to participate in the control of the GBM neonatal vascular formation process, thereby promoting GBM cell proliferation, invasion and migration.38 The gene discussed is GSK3A; the disease is glioblastoma.